Best and Effective Alternatives to Adderall

Best and Effective Alternatives to Adderall

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Picture of Arooj Anjum

Arooj Anjum

Biomedical Engineer

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Adderall has significant benefits in treating ADHD. But, we all know that medications for mental health conditions like SSRIs, SNRIs, Lexapro, Xanax, etc, have adverse side effects (like increased heart rate), potential for misuse, and lead to dependency. The same is true for Adderall. The proper dosage is essential. Find out more here.

 

People are wondering, are there any alternatives to Adderall? The good news is, yes, there are some natural alternatives and other prescription drugs/drugs.

 

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What is Adderall?

 

Adderall is a prescription stimulant medication used for treating attention deficit hyperactivity disorder (ADHD). Stimulating drugs work by altering the levels of neurotransmitters in the brain. These neurotransmitters help increase attention, allowing people to stay organized and focused. In the end, everything helps them complete tasks on time.

Prescription Drugs- Alternatives to Adderall

 

People are wired differently. That’s why some medications (regardless of how good and effective they are) do not suit an individual. If you are among that group of people who want alternatives to Adderall because, let’s say, the side effects are harsh, or maybe you are not getting the desired result, then keep reading. You should switch to ginkgo biloba or any less potent central nervous system stimulant with fewer side effects, or lifestyle changes might help.

 

There are other treatment options like stimulants, non-stimulant drugs, and natural supplements as alternative treatments, which you can discuss with your healthcare professionals.

1. Strattera (Atomoxetine)

 

Strattera, or atomoxetine, is a non-stimulant drug used to manage attention-deficit hyperactivity disorder symptoms. It is different from other stimulant drugs (Vyvanse, Adderall, and Ritalin) that directly stimulate the release of dopamine and norepinephrine in our brains. 

 

Strattera selectively inhibits the reuptake of the neurotransmitter norepinephrine, which is responsible for impulse control and attention. Strattera is the brand name for atomoxetine salt. The critical benefit of atomoxetine is that being a non-stimulant, it has less tendency for dependency and abuse. It makes it suitable for people who are at high risk of substance abuse disorder or individuals who want to avoid stimulant drugs.

 

Key Differences

  • Strattera is a non-stimulant; it has a different mode of action than stimulants like Adderall. 
  • Another difference is Strattera does not lead to potential adverse effects like palpitations and insomnia.
  • Finally, the results after taking Strattera were quicker than Adderall’s results, which takes several weeks for significant changes to become visible.

Dosage Guide

  • Strattera is available in the form of capsules. 
  • The dosage for ADHD depends on the age and weight of the individual.
  • For people >6- years old and weighing more than 70 kg, 40 MG once a day.
  • After three days, the dose is increased to 80 mg once they are 40 MG twice/day.
  • The doctor will determine the dosage for children and adults > 6 years and weighing <70 kg, depending on the body mass index.

2. Qelbree (Viloxazine)

 

The second alternative to Adderall is Qelbree. It is another non-stimulant medication used once daily for managing the symptoms of ADHD, along with other treatment plans, including behavioral therapy and ABA therapy.

 

A key benefit of Viloxazine is that it is not a controlled substance, making it safe for people to use for long-term use. It is free from side effects like trouble sleeping, and finally, it has no withdrawal symptoms; it does not lead to abuse or dependence, making it a safer option. Like all medications, Qelbree has side effects, too, but they are manageable.

 

Key Differences

  • Adderall is a stimulant drug with comparatively short-acting results. It is taken once or twice a day. 
  • Adderall is a controlled drug and has a high potential for misuse, dependency, and abuse. In comparison, 
  • Qelbree has no such issue.

Dosage Guide

  • The dosage of Qelbree for adults during the first week is 200 MG/day. After careful monitoring, the doctor will increase it, if needed,  to a maximum of 600 MG/day.
  • The dose for children may vary between 100 and 400 MG per day, depending on the seriousness of the condition.

3. Intunive (Guanfacine)

 

Guanfacine is yet another non-stimulant drug for the treatment of ADHD. Guanfacine was initially invented to manage high blood pressure; Intunive is available only in an extended-release form. Its mode of action affects the  alpha-2A receptors in the brain ( prefrontal cortex) responsible for regulating attention and impulse control. 

 

Key Differences

  • Unlike Adderall, which increases the levels of norepinephrine and dopamine in the brain, Guanfacine only targets specific parts of the brain, which leads to fewer side effects. You will get signs when your Adderall dose is low.

Dosage Guide

  • The dose of this medication depends on various factors, so only your doctor can help you decide which age is best for managing ADHD symptoms.

4. Retalin (methylphenidate)

 

Ritalin’s mode of action is similar to Adderall’s. It impacts the neurotransmitters in the brain, namely dopamine and norepinephrine. Changes in the levels of these neurotransmitters affect hyperactivity and impulsivity in people who have ADHD. It then improves brain function and helps the person focus more and be more attentive. Some studies suggest that Adderall is more potent than Ritalin, and you can get a similar effect on low doses of Adderall.

 

Key Differences

  • The significant difference between Adderall and Ritalin is the salt. 
  • The absence of amphetamine in Ritalin makes it more tolerable with your side effects. It makes it an effective alternative to Adderall.

Dosage Guide

  • The starting dose for adults is 20 MG to 30 MG/ day, with a maximum of 60 MG per day.
  • For children, the starting dose is 5MG taken twice daily. The doctor will decide the final dosage based on the symptoms.

5. Provigil (Modafinil)

 

Initially, for the treatment of narcolepsy, Provigil is sometimes used as off-label for the treatment of attention deficit hyperactivity disorder. Modafinil helps enhance cognitive function and focus. Like other stimulants, it comes with its own set of side effects. Although milder Adderall, the chances of it triggering anxiety, irritability, and agitation are less.

 

Key Differences

  • Provigil varies in its structure and is not a stimulant like Adderall, which is why the side effects are only mild.
  • Unlike Adderall, which is a Schedule 2 controlled substance, Provigil is a Schedule 4 controlled drug. Therefore, the chances of abuse and dependency are a little less than with Adderall.

Dosage Guide

  • Provigil is used off-label for treating ADHD symptoms. 
  • Your mental healthcare provider will prescribe a low dose, between 50mg – 100mg. Some patients may require a higher dose.

6. Focalin (dexmethylphenidate)

 

Just like Adderall, Focalin is a central nervous stimulant that raises the levels of dopamine and norepinephrine in the brain. These messengers are responsible for sending messages between the nerves, and it is believed that an increase in levels can effectively improve impulse control and wakefulness in people who have ADHD. Although the mechanism of action of both are the same, there are some significant differences.

 

Key Differences

  • Focalin is an alternative to Adderall. The first significant difference between the two is the active ingredients. 
  • The main ingredient in Focalin is dexmethylphenidate, similar to Ritalin, while the active ingredient in Adderall is the amphetamine salts. 
  • Another difference is the age brackets they used for. Focalin is better suited for children, while the latter is for adults.
  • Adderall side effects are depression, whereas not for Focalin.

Dose Extended-release Form Capsules

  • The adult dose for ADHD is 10 MG/ day, preferably in the morning. 
  • The maximum dose is 40 MG.
  • For children over six years of age, the ideal dose is 5MG/ day. 
  • The maximum dose should not exceed 30 MG.
  • For children <6, the doctor will decide the dose.

Tablet Form

  • The initial dose for adults and children over 6  is 5MG, divided into 2.5 MG twice/day. 
  • The maximum dose should not exceed 10mg twice a day.
  • Make sure there is a four-hour difference between the drug administration.
  • For the younger children, the doctor will decide the dose.

7. Vyvanse (amphetamine.-Dextroamphetamine)

 

This drug is the most similar alternative to Adderall. The potential side effects, its efficiency in treating the disease, and the risk of abuse are almost the same. Researchers believe that Adderall has a high potential for dependency and abuse. It is essential to use the drug as prescribed to keep the side effects away. If you feel the side effects are bothersome, probably, the Vyvanse dose is too high. Remember, it is a controlled drug, and using it long-term is not recommended.

 

There are many similarities and differences between Vyvanse and Adderall, but the most significant difference is the active ingredients. When someone takes Vyvanse, they convert it into dexamphetamine, which is why it takes longer for it to show visible results.

 

Dose

  • The starting dose of Vyvanse for adults is 30 MG/day, and the maximum is 70mg.
  • The starting dose for children is 30 MG. The final dose depends on the symptoms and how well the medicine is tolerated.

8. Alternative to Adderall Therapy

 

There are different types of therapies available for managing the symptoms of ADHD. Cognitive behavioral therapy for ADHD is one of the most common types of therapy used that has helped people in the past as well. Another therapy is ABA therapy for ADHD. Therapy instills positive behaviors in the patients. In some minor cases of ADHD, therapy alone can be beneficial for the treatment.

OTC Alternatives to Adderall

 

Sometimes, medication is not an option for individuals who have ADHD. They want some alternatives to Adderall, and this is where OTC over-the-counter alternatives are beneficial.

9. Nootropic Supplements 

 

Nootropic supplements are available as stimulant and non-stimulant supplements. Some of them are available over the counter as well and are beneficial in managing the symptoms of ADHD. These supplements improve mental functions. Like memory, cognitive functioning, motivation, alertness, focus, and learning people, some joint OTC nootropic supplements are;

  • Creatine: although few studies have been done, it is believed that the amino acid in creatine improves brain health and functioning, including cognitive processing.
  • Resveratrol is a naturally occurring ox found in the skins of purple and red fruits like grapes and blueberries. Some studies suggest that they have the characteristics to improve the symptoms of ADHD.

10. Caffeine Pills

 

There are mixed results on whether coffee or caffeine used as stimulants are good enough for managing the symptoms of ADHD. Some people suggest that consuming tea with caffeine has a positive effect on individuals who have ADHD. It is one of the best natural Adderall alternatives. 

11. Herbal stimulants

 

Some people want to try the holistic approach to managing the symptoms of ADHD. For them, herbal stimulants are the best bet. Although more research is needed, some herbal supplements that have shown promising results are;

  • Ginseng: this herbal supplement is widely used in China to enhance energy and promote brain function. Red ginseng enhances hyperactivity in children who have ADHD. According to one study, people who took ginseng for eight weeks showed improvement in their anxiety and social functioning. Another study suggested combining Korean red ginseng with omega-3 fatty acids improves memory and attention issues in children with ADHD.
  • Guarana: According to research, this herbal supplement has active ingredients and some 
  • caffeine content that helps with cognitive performance.

12. Vitamins and Minerals

 

The lack of minerals and vitamins makes it challenging to manage the symptoms of ADHD, especially Magnesium and Zinc.

  • Magnesium: Experts found a link between low magnesium levels and higher chances of ADHD. Although magnesium cannot improve attention, the proper levels help reduce hyperactive behaviour.
  • Zinc: Although not many studies have been conducted on this, some studies suggest that low levels of Zinc increase the likelihood of ADHD development.

The Bottom Line

 

If Adderall doesn’t suit you, don’t worry. We just mentioned a handful of alternatives to Adderall. All these are effective on its own. With different side effects, active ingredients, and mechanisms of action, only your healthcare professional can decide which ones for you.

 

If you want to learn more about alternatives to Adderall, contact us and talk to the experts themselves. They will guide you toward the treatment options, offer medical advice, customize a treatment plan, and prescribe the best medication for your symptoms.

 

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Sometimes the mind races in a hundred directions, but with the right focus, it can lead to extraordinary paths.

FAQ

1. What is the best alternative to Adderall during a shortage?

 

If you are looking for a non-stimulant drug,  then your best option would be Straterra, Guanfacine, and Clonidine.

2. Is Ritalin better than Adderall?

 

Both are effective on its own. However, Ritalin is better suited for children and Adderall for adults. Adderall might cause sudden death in children and teens, especially in individuals with heart conditions.

3. Is caffeine an effective alternative to Adderall?

 

According to a few studies, caffeine has been shown to improve the symptoms of ADHD.  Although, it is not used as a replacement for ADHD because it can not replace the effectiveness of prescription drugs.

4. How do stimulants calm people?

 

Stimulants boost serotonin, dopamine, and norepinephrine levels in the brain. These neurotransmitters are responsible for inducing calming and relaxing effects.

 

Additional Resources

Vyvanse vs Adderall for ADHD

ADHD Paralysis

ADHD Mood Swings in Adults and Children

Does Caffeine Help ADHD Symptoms?

Adderall interacts with vitamin C

How to Get Prescribed Adderall

Blue Adderall Pill Withdrawal Effects

How Long Does Adderall Stay in Your System

Ultimate Guide to Normal Adderall Dosage for Adults & Children

Signs Your Adderall for ADHD Dose is Too Low

Review of Top Over-the-counter Adderall Alternatives 

Adderall XR Dosage, Forms, and Strengths

6 Common Reasons for Adderall Not Working

Compare Adderall Coupons and Prices

Can Adderall for ADHD Cause Depression?

How Long Do Adderall Headaches Last?

Common Adderall Effects on Personality

Working Out on Adderall

Adderall Generic

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