Comparison Between Dexedrine vs. Adderall for ADHD

Dexedrine and Adderall are both stimulant medications used for attention deficit hyperactivity disorder. The main chemicals in this prescription medication are as follows; 

1. Dexedrine- dextroamphetamine and 
2. Adderall – amphetamine.  

The FDA approves both drugs to treat narcolepsy and ADHD. When the correct drug administration method is used, it helps in reducing ADHD symptoms. It helps the person to focus and concentrate, decreasing impulsive and hyperactive behavior.

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Dexedrine vs Adderall for ADHD Treatment

ADHD stands for attention deficit hyperactivity disorder. It is generally diagnosed in early childhood and remains throughout adulthood. The following are the symptoms of ADHD look for out;

• Difficulty in focusing and maintaining attention
• Impulsive behaviors
• Getting easily distracted by external stimuli
• Symptoms of inattention and hyperactive behavior.

How to Get Prescribed Adderall?

Before your doctor prescribes Dexedrine vs Adderall for ADHD treatment, they might try other treatment options like;

1. psychotherapy,
2. behavioral therapy, like ABA therapy
3. and educational training. 

If all fails, then they will turn to drugs. Although the FDA approves all medicines for ADHD treatment, some of them contain a boxed warning that indicates that misuse of amphetamines can cause death or, at times, lead to severe cardiovascular reactions.

Note: All mental healthcare professionals should screen the candidate for potential heart problems before they prescribe Adderall versus Dexedrine. 

According to the manufacturers of ADHD medicines, the following contradictions are possible;

• Symptomatic cardiovascular disease
• Advanced arteriosclerosis 
• Moderate to extensive hypertension
• Hyperthyroidism
• Glaucoma
• Hypersensitivity to the sympathomimetic amines
• And, at times, agitated states.

Other ADHD Medications

Some other drugs that your doctor may prescribe are;

• Qelbree
• Ritalin
• Vyvanse

For a same-day Adderall prescription, call us at [Direct]. After the initial evaluation, your online doctor will prescribe Adderall or a refill. 

Similarities & Differences Between Dexedrine and Adderall

Dexedrine and Adderall are both synthetic compounds containing the salt amphetamine, a central nervous system stimulant. The exact mode of action is still unknown by the researchers. However, it is thought that when someone takes Dexedrine vs. Adderall, it increases the release of serotonin, norepinephrine, and dopamine, which are the body’s neurotransmitters.

The main difference between Dexedrine and Adderall is that the latter contains amphetamine and dextroamphetamine, whereas Dexedrine contains dextroamphetamine. Both consist of different forms and ratios of amphetamine but are equally effective medicines for treating ADHD  used since the 1970s.

• Dexedrine consists of the active ingredient d-amphetamine, whereas Adderall contains three parts of the immediate release d-amphetamine part of amphetamine. 
• The extended-release version of Adderall, such as Adderall XR, contains equal portions of immediate-release, delayed-release D-amphetamine, and I-amphetamine.
• Dexedrine is also found in a sustained-release formula containing the time-release d-amphetamine. (Dexedrine Spansule).
• Presently, the immediately released type of medication for Adderall and Dexedrine is approved by the FDA for the treatment of ADHD in children aged three years and older.
• In contrast, the extended-release Dexedrine vs. Adderall XR is not approved for children under six years of age, and Dexedrine Spansule is not approved for people over 16.

Mechanism of Action 

Although the exact mechanism of action is unknown, the medications are believed to make the neurotransmitters last longer in the brain’s parts and be responsible for alertness and attention. They are also thought to increase the concentration of these neurotransmitters in the brain.

Neurotransmitters are chemical messengers that convey a message from one brain cell to another. When someone takes these drugs, it makes the area more active, and the drug allows the person to focus their attention.

Forms, Strength, and Dosing of Dexedrine Versus Adderall

Dexedrine vs Adderall are available in the following forms:

1. Dexedrine IR comes in tablet and solution forms.
2. Adderall IT is available in tablet form.
3. Dexedrine and Adderall XR or extended-release capsules are found as capsules only.

The extended-release formula has a lasting effect and is mostly favored by doctors. In contrast, the immediate-release option is better for rapid relief.

Dexedrine Dosage 

The usual dose for Dexedrin vs. Adderall is one tablet/day. If your doctor prescribes Dexedrine, the initial dose would be between 2.5 MG and 5.0 MG daily. The dosage will then be adjusted slowly.

Dexedrine is taken daily in doses between 5MG and 60MG for adults and 2.5MG to 40MG for children. It is available in different forms and strengths, such as extended-release forms.

Adderall Dosage Guide

In contrast, the starting dose for Adderall is 5MG per day and can be slowly adjusted by the doctor. The maximum is 40 MG and 60 MG per day. The starting rate for children is 2.5 MG, gradually increasing to 40 MG per day. 

Like Dexedrine, several strengths are available, and an extended-release form makes it easier to find the proper dosage. However, it would help if you had a doctor’s prescription to take this medication. Learn from the medical-oriented guide on Adderall dosage. 

How Much Does Adderall and Dexedrin Cost?

Both Adderall and Adderall are expensive medications used to treat ADHD. However, you can go for the generic form/version, which is usually cheaper than the brand name, which costs more than $300 for Adderall and more than $849 for Dexedrin. Talk to your doctor about taking the generic version; it’s as effective as the brand name. 

Serious Side-Effects of Dexedrine vs Adderall

Like all stimulant drugs, Adderall versus Dexedrine comes with its potential side effects. One common side effect for both is high blood pressure. Although minor, this blood pressure can be fatal for people suffering from hypertension and heart problems. 

So, if you suffer any of these medical conditions, discuss the risks and benefits of Adderall and Dextrin before you start taking the medication.

Some of the side effects of Adderall versus dexedrine are;

• Burning while urination
• Diarrhea or constipation
• irregular heartbeats or palpitations
• Dry mouth
• Weight loss
• Loss of appetite
• Reduced growth in children
• Insomnia or sleep disorder
• Impotence
• Depression

Although rare, Adderall could also result in alopecia, which is a hair loss condition on the scalp and other parts of the body.

Adderall Versus Dexedrine: Warnings and Interactions

Your healthcare provider will initially prescribe a low dose of prescription drugs to avoid possible overdose, withdrawal symptoms, or side effects.

Although it’s rare, Adderall versus Dexedrine can lead to a medical condition that affects the blood vessels of your fingers, hands, feet, and legs. This condition is known as peripheral vasculopathy. If you have already started the treatment plan for these medications and you feel that your fingers, toes, etc., are getting numb, ticklish, and cold, and you notice an unusual wound on your fingers and toes, consult your doctor immediately.

Before you start the treatment plan, tell your doctor about any pre-existing psychiatric issues and seizure disorders. Using these medications along with ADHD medicines can worsen the symptoms.

Some people taking Adderall have noticed motor tics and changes in speech. In this case, your medical professional will alter the dosage or switch to another medication to reduce symptoms. 

Adderall versus Dexedrine both have a high potential for substance use disorder. Therefore, long-term uses of this medication have been associated with psychological dependence. If you have a history of substance abuse, these medications may not be the right fit for you. In any case, ensure that you keep these medicines away from the reach of children or keep them locked in the cabinet.

Pregnancy and breastfeeding: Not many studies have been done on how these drugs affect breastfeeding women and pregnant women. However, amphetamines can be dangerous for the developing fetus; for example, it can lead to premature birth and lower birth of the baby. It happens even if the dose of amphetamines is low.

Some studies also show a risk of behavioral problems in children; for all, nursing mothers do not take Adderall versus Dexedrine as it can pass through the breast and be toxic to the baby.

Drug Interactions of Adderall Versus Dexedrine

The presence of amphetamines in both these drugs can react negatively with many medications;

• Do not take anti-seizure medications like phenobarbital, ethosuximide, or phenytoin, as amphetamines react negatively with these. 
• These drugs block the sedative effects of all the antihistamines used in allergy medications.
• If you are taking medication to reduce blood pressure, avoid using Adderall versus Dexedrine, as it loses its effectiveness if either of these medications is taken.
• If you have a pre-existing medical condition and you take antipsychotic medication like Xanax, Lexapro, or any other SSRIs while taking this ADHD medication. It can impose a risk of complications.
• If you take either Adderall vs. Dexedrine or any other ADHD medications like Qelbree or Vyvanse, then make sure you do not take the following drugs without consent from your medical healthcare provider as these supplements reduce the effectiveness of the ADHD drugs;

Also, avoid the following;

• over-the-counter medication
• Supplements
• Vitamins
• Herbal supplements
• Iron or fluoride 
• Antacid, 
• Antibiotics
• Monoamine oxidize inhibitors MAO inhibitors
• Proton pump inhibitors increase the drug level of ADHD drugs, leading to a dangerous reaction.

Note: Make sure you provide the complete list of all the medications you take to your doctor if they prescribe either of these drugs to you.

Also, if you are concerned, ask your pharmacist about any potential side effects, adverse reactions, warnings, or health risks associated with these medications.

The Bottom Line

To summarise, both medications’ effectiveness and safety profiles are similar. However, as all individuals respond differently to each medication, either of these drugs works well for you. 

However, Dexedrine is stronger than Adderall in the sense that its effects are more pronounced in the brain, which can also lead to more side effects. In contrast, Adderall has a long-lasting, stable effect on the brain. In the end, which one suits you better depends on how your body responds to these drugs.

Medical Disclaimer:

At TherapyFleet, we strive to enhance the quality of life for those dealing with mental health issues. Our licensed medical professionals meticulously research, edit, and review all content before publication. Nonetheless, this information should not replace professional medical advice, diagnosis, or treatment. For medical guidance, please consult your physician or reach out to TherapyFleet’s qualified staff.

Embrace your unique path and trust in your ability to overcome challenges. Every step forward, no matter how small, brings you closer to your goals.

FAQs

1. Is Dexedrine Still Prescribed Now?

Dexedrine is one of the oldest medications used for treating ADHD. As mentioned earlier, it is a strong drug. Now, the market has new & safer medications. However, your doctor will prescribe it if they feel that you need a more potent medication to treat your symptoms.

2.    Why Don’t Doctors Prescribe Dexedrine?

It has a high potential for abuse, and it can lead to serious heart and blood pressure problems. Therefore, Dexedrine is habit-forming and is rarely prescribed now.

3.     Is Dexedrine an Effective Medication?

Yes, it can improve focus and concentration and reduce the symptoms of hyperactivity, impulsivity, etc. It is also used for treating narcolepsy in adults.

4.    Is Ritalin Better than Dexedrine?

The latter’s average rating is 8.6 out of 10, while Ritalin’s is 7.0 out of 10. However, in terms of effectiveness, we cannot say which is better because it all comes down to the individual’s response to the medication. 

Both Ritalin and Dexedrine have different active ingredients and work differently, so choosing which one is better than the other is just not fair.