Effects of Bupropion for Anxiety & Depression

Effects of Bupropion for Anxiety & Depression

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Picture of Arooj Anjum

Arooj Anjum

Biomedical Engineer

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Are you living your life in anxiety? Are you searching for ways to manage your anxiety? Anxiety is a crippling disease, and it can ruin your lifestyle. Many medications are used for treating anxiety disorders, but in this blog, we are going to talk about bupropion for anxiety. If you suffer from mental health conditions and want a way out of it without going out and waiting in long queues, then your search comes to an end. 

 

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What is Bupropion (Wellbutrin)?

 

Wellbutrin is an anxiety medicine commonly known as bupropion. It is used to treat more disorders like depression and seasonal affective disorder. Although off-label use of bupropion has shown effective results in treating attention deficit hyperactivity disorder, it has also shown promising results for people who want to quit smoking and for social anxiety.

Mechanism of action

 

Wellbutrin belongs to a class of drugs that are known as aminoketones. When someone takes bupropion for anxiety, it enhances the production of two neurotransmitters in the brain, namely norepinephrine and dopamine. Dopamine is responsible for elevating different body functions like sleep mode and motivation. Also known as a reward center, the right dopamine levels are important, as a lack of it can cause Parkinson’s disease and restless leg syndrome. Norepinephrine is a natural hormone and an agent in the brain’s central and peripheral nervous system that is responsible for sending nerve signals. High norepinephrine levels keep you focused and alert by pumping blood.

 

Wellbutrin is available in the form of capsules that you take orally. There are two forms: immediate-release and extended-release tablets. Most often, bupropion is found in the pharmacy as forfivo XL and Aplenzin.

Using Bupropion for Anxiety

 

Although initially approved by the FDA for the treatment of depression as an antidepressant medication, research shows that bupropion for anxiety is as effective. In another study, bupropion drastically improved the symptoms of anxiety in people. The results were similar to Zoloft, which is commonly used for anxiety disorders. 

 

Several more studies suggested that bupropion for anxiety is an appropriate drug for people suffering from comorbid anxiety. This becomes possible because bupropion is quite effective in reducing depression-related anxiety symptoms in individuals suffering from anxiety disorder. Further studies suggested that bupropion has anxiety-reducing effects in people with clinical depression.

 

However, more research needs to be done to understand how it works to reduce stress. However, a pilot study was performed that showed promising results. The study compared the efficacy of bupropion with SSRI selective serotonin reuptake inhibitors, which are used to treat depression and anxiety with generalized anxiety disorder (GAD). The results showed that bupropion was well tolerated in reducing stress, and the results were the same treatment as escitalopram.

Does Bupropion for Anxiety Increases Anxiety?

 

There is a little myth and confusion among people that bupropion for anxiety induces anxiety. But is it true? Let’s find out.

 

Unfortunately, the answer is yes. One of the most common side effects of bupropion for anxiety is that it can induce anxiety symptoms in some people. The risk is the same as the other antidepressants like SSRIs and SNRIs. All anti-depressants are prone to causing anxiety. Although 1 in 10 people suffering from depression can have anxiety induced by using bupropion

 

Did you know that bupropion for anxiety is the fourth most commonly prescribed antidepressant? So, suppose you have been prescribed bupropion for anxiety by your mental health professional. In that case, start using it as directed, and do not worry about the induction of anxiety as anxiety symptoms being developed are rare.

 

In contrast, Wellbutrin has fewer side effects than other antidepressants. You don’t have to worry about weight gain, reduced energy, apathy, and poor sexual performance.

Optimal Dosage of Wellbutrin for Anxiety 

 

As mentioned earlier, Wellbutrin for anxiety is available in the form of Wellbutrin SR, which is slow release, and Wellbutrin XL, extended-release. The optimal usage of Wellbutrin for anxiety varies from person to person. 

 

Follow the exact instructions offered to you by your mental health professional or doctor.  If you are unsure how to use the medication, it’s always better to ask. Do not hesitate.

 

Before using the medicine, you should know how often you need to take it and what you need. The side effects of the drug interactions and the risk of Wellbutrin for anxiety.

 

Wellbutrin for anxiety is available in different doses. The immediate-release form comes in 75MG and 100 mg, and the extended-release form comes in 100 MG, 150 MG, 200 MG, 300 MG, and 450 MG in a single tablet. However, the final dose potency depends on the brand you are using.

 

Bupropion is available in several doses, and there’s a fairly standard understanding of how much medication should be taken for depression treatment. The starting dose of Wellbutrin for depression is 150 MG per day, and the maximum number of doses can go up to three times per day. However, as mentioned earlier, it depends on the patient.

 

In contrast, the dose for anxiety will be lower than the dose for depression. Not many studies are done on the appropriate dose for anxiety, so at this level, it is considered to be experimental.  Some healthcare professionals believe the low and slow approach is the best. That is, the recommended dose should be half of that of depression.

Cost of Wellbutrin for Anxiety

 

Wellbutrin for anxiety does not come without a prescription, so you need to see a doctor first. Seek medical advice to get a prescription for anxiety. The cost of anxiety depends on your dose, your local pharmacy, and the details of your insurance agency. If you are paying from your pocket, 30 tablets of bupropion immediate-release 75MG is around $35.

 

The out-of-pocket price of the brand Wellbutrin SR is around $549 for 60 tablets of 150 MG.Out of the pocket price of extended-release dollar 2900 tablets MG; therefore, it is always better to go for the generic version and not the brand name.

 

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Potential Side Effects of Bupropion for Anxiety

 

Like other antidepressants and medicines for anxiety, Wellbutrin comes with side effects, too. So, if you suffer from other medical conditions, consult your doctor.

 

Some common side effects are 

  • Weight loss 
  • Headache 
  • Dry mouth
  • Nausea 
  • Insomnia 
  • Business 
  • Rapid heartbeat 
  • Constipation 
  • And sore throat 

Although rare, bupropion can also lead to some serious side effects. In case any of the following side effects occur, do not hesitate to call your medical doctor, or in case of an emergency, call 911

  • Sweating 
  • Ear ringing 
  • Skin rash 
  • Muscle pain 
  • Shakiness 
  • Stomach pain 
  • Changes in thought pattern 
  • Pen swelling and redness in the eye 

Drug Interactions

 

Do not keep any medical history from your doctor. Wellbutrin can have some serious drug interactions. Make sure you list down all the medicines you take regularly before going to your appointment. This includes supplements, vitamins, and over-the-counter meds. The following medications can have serious reactions when taken alongside Wellbutrin.

Specific Antidepressants

 

Monoamine oxidase inhibitors, or MAOIs, are antidepressants that should be avoided when on Wellbutrin. This combination is lethal and can increase the blood pressure to dangerous levels. Some other antidepressants to avoid are imipramine, sertraline, and venlafaxine, which could increase the risk of seizures.

Antipsychotic Medications

 

If you are on any antipsychotic medication, make sure you tell your doctor. Bupropion interacts with some antipsychotic drugs and leads to adverse reactions.

Heart medication

 

Tell your doctor if you suffer from heart disease and are taking any heart medications, such as beta-blockers or antiarrhythmics. Wellbutrin combined with these heart drugs can cause low blood pressure and impact your heartbeat. Medical professionals are likely to lower the dose of Wellbutrin.

Corticosteroids

 

Using Corticosteroids alongside bupropion for anxiety increases the occurrence of seizures. Keeping any medical history can result in dangerous reactions. So make sure you tell your doctor about any medication you take so that they can adjust the Wellbutrin dose accordingly.

Blood Thinners

 

Wellbutrin and blood thinners are not safe together. Tell your healthcare provider if you regularly use blood thinners.

Anti Seizure Drugs

 

When combined with Wellbutrin, antiseizure medication can lower the latter’s effectiveness. If you take any drugs regularly, tell your doctor to adjust the dosage so that both work equally.

 

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Is Bupropion for Anxiety Suitable for Me?

 

The first thing a doctor will check is whether bupropion for anxiety is the best medicine for you. He will check your symptoms, frequency of anxiety attacks, and present health condition.

 

If all goes well, he will prescribe bupropion to you. It may be a good fit, 

 

  • If you were on another an anxiety and the side effects were severe for you, the doctor would probably describe Wellbutrin as it has fewer side effects. 
  • If you also need help to quit smoking
  • If you suffer from major depressive disorders and anxiety and if you are looking for long-term treatments

Before You Start Wellbutrin

 

If anxiety and depression are taking a toll on your life and are affecting your mental and physical health, it’s time to seek help. Talk to your healthcare provider for medical advice. Ask them if Wellbutrin is an option for you. All medicines have side effects; contact your doctor if you suffer from the following. 

  • Suffer from high blood pressure.
  • Seizures
  • You have suicide
  • Anxiety or depressive symptoms
  • Your heart changes
  • Swelling and pain in the eye

Conclusion

 

Bupropion for anxiety is effective in reducing the symptoms of anxiety in people, just like clonidine. With the right drug administration and proper treatment plan, people feel better with time. Wellbutrin, as compared to other medications, has fewer adverse reactions and drug warnings. So, a safer option to go for. Contact your healthcare professional if you suffer from mood disorders and anxiety problems. 

 

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Medical Disclaimer:

 

At TherapyFleet, we strive to enhance the quality of life for those dealing with mental health issues. Our licensed medical professionals meticulously research, edit, and review all content before publication. Nonetheless, this information should not replace professional medical advice, diagnosis, or treatment. For medical guidance, please consult your physician or reach out to TherapyFleet’s qualified staff.

 

Bupropion can be effective for depression but may not alleviate anxiety for everyone. Individual response can vary, so it’s crucial to discuss with a healthcare provider to find the best treatment approach.

FAQs

1. How much time does bupropion for anxiety take to show results?

 

Unlike Ativan and Xanax, Bupropion for anxiety takes time to show visible results. Expect around a couple of weeks for the medicine to show its magic. It might take up to four weeks for complete effect and control over the anxiety symptoms.

2. Does anxiety caused by Wellbutrin fade?

 

Anxiety caused by antidepressants usually does not last more than a week or two. These side effects are rare, meaning not everyone taking Wellbutrin for anxiety suffers from anxiety induced by the drug itself.

3. Will bupropion make me sad?

 

All antipsychotics come with some common side effects. For Wellbutrin, the potential side effects are; Agitation, suicidal thoughts, and depression. However, these symptoms will resolve soon. But, if they don’t and you don’t well and have suicidal thoughts, contact your healthcare provider as a priority.

4. Is Bupropion good for panic disorders?

 

Some evidence does suggest that bupropion for anxiety shows good results for people with panic disorder.

5. Is Bupropion for anxiety an effective type of antidepressant?

 

Wellbutrin or bupropion has shown promising results in reducing anxiety levels. Apart from being an effective antidepressant, bupropion has many more benefits for anxiety patients, too. The best part about Wellbutrin is that, like other antidepressants, it is free of common side effects like weight gain.

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