Hydroxyzine for Sleep: Dosage, Benefits, and side effects

Hydroxyzine for Sleep: Dosage, Benefits, and side effects

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Picture of Aisha Bibi

Aisha Bibi

Clinical psychologist

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Hydroxyzine is an antihistamine that helps with sleep by reducing anxiety. Learn about its dosage, benefits, side effects, and precautions before use.

Hydroxyzine for Sleep: Dosage, Benefits, and Side Effects

Hydroxyzine is a medication used to treat itching or hives caused by an allergic reaction. It belongs to a class of drugs called antihistamines. Hydroxyzine works by blocking the effect of histamine, a substance released by the body that promotes an allergic reaction. It also has sedative effects, which means it induces sleepiness and, therefore, is used as a sedative to relieve anxiety and tension in children and adults.

Hydroxyzine is not FDA-approved for the treatment of insomnia, but may sometimes be prescribed as a sedative. Only a licensed healthcare provider can determine the effective dosage of the medications.

If you are struggling with sleep issues, anxiety, or stress, consult your doctor to discuss your symptoms and receive the right treatment plan tailored to your specific needs.

Prevalence of Sleep Deprivation in the United States

  • Many people in the United States face the problem of sleep deprivation. 1 in 3 Americans doesn’t get enough sleep they need to maintain their mental health.
  • Studies found that nearly 14.5% of adults experience difficulty falling asleep most days or daily. (2020)
  • Women (17.15%) are more likely to experience difficulty falling asleep compared to men (11.7%)

That is why many people start taking medication to improve their sleep. One such medication is Hydroxyzine. However, consulting a doctor is essential before taking any new medication. 

What is Hydroxyzine and is It Used for Sleep?

Hydroxyzine is an antihistamine used to control itching caused by allergies. It is FDA-approved for the treatment of anxiety (short-term treatment of anxiety and stress) or as a sedative before and after anesthesia. 

While it has sedative effects, causing drowsiness and sleepiness, this does not mean it is officially approved for sleep. Doctors may sometimes prescribe it off-label for sleep, particularly when insomnia is due to anxiety. However, it is best to consult a doctor before using it for sleep issues or insomnia.

Hydroxyzine comes in the following forms:

  1. Tablet
  2. Capsule
  3. Syrup

Follow the doctor’s advice and take it as prescribed to ensure safety and effectiveness.

How Does Hydroxyzine Work for Sleep?

Imagine that your body has worry signals triggered by a chemical messenger named Histamine. Hydroxyzine works like a blocker. It blocks the worry signal and reduces the body’s sensitivity to these signals, leading to drowsiness. It helps with allergies and sleep problems. Hydroxyzine provides relief to individuals who experience sleep disturbances as a result of anxiety or stress.

Dosage Guidelines of Hydroxyzine for Sleep and Anxiety

1. For anxiety relief

i. Children

The dosage for children may depend on body weight. A typical dose for children is 2 mg/kg per day, divided into 3 or 4 doses.

ii. Adults

For adults, it’s 50-100 mg taken up to 4 times a day.

2. For Allergic reactions

i. Children

The dosage for children is 50-100mg daily

ii. Adults

For adults, it is 25mg twice or thrice daily

3. As a sedative

i. Children

The recommended dose for children is 0.6 mg/kg orally

ii. Adults

For adults, it is 50-100mg.

It is always essential to consult your doctor before taking Hydroxyzine. Only a licensed healthcare provider can determine the right dosage for you or your child. Self-medication can lead to overdose, misuse, and serious harm.

Overdose of Hydroxyzine

If you have taken more medication than prescribed (overdose), you may experience symptoms such as:

  1. Nausea and vomiting
  2. Severe drowsiness
  3. Tremors
  4. Loss of consciousness
  5. Blurred vision
  6. Seizures (in severe cases)

If you suspect an overdose, call 911 immediately (for the U.S) or seek emergency medical attention at the nearest hospital.

 

Note: Hydroxyzine can cause drowsiness and impair coordination. Avoid activities like driving or operating heavy machinery while taking Hydroxyzine to prevent accidents or injuries.

Missed Dose of Hydroxyzine

Do not double the dose if you have missed a dose of Hydroxyzine. Skip the missed dose if it’s time for your next dose; you may take it at your regular time.

If you miss a dose, you can take it if it’s not close to your next scheduled dose.

 

Ask an Expert!

Is Hydroxyzine safe for breastfeeding?

Hydroxyzine is not commonly recommended as the first choice for breastfeeding mothers, especially with newborns or for long-term use. It may be acceptable to use in small doses occasionally, but it carries a potential hazard to milk production and the baby’s health.

The primary concerns are:

  • Hydroxyzine reduces milk production.
  • It may cause drowsiness, sedation, and irritability in the baby.

It is essential to use other safer antihistamines, or short-acting sedatives like lorazepam or mirtazapine under medical supervision, as they pose a lower risk.

5 Benefits of Hydroxyzine for Sleep

  1. Hydroxyzine is an antihistamine and has calming and sedative properties. Hydroxyzine helps individuals fall asleep faster.
  2. Depending on the dose, Hydroxyzine can help individuals to sleep for longer.
  3. According to studies, Hydroxyzine can be considered for short-term treatment of insomnia.
  4. Hydroxyzine is not habit-forming like other sedative medications, such as benzodiazepines, such as lorazepam, alprazolam, and diazepam.
  5. Hydroxyzine helps to control anxiety and improve sleep.

13 Possible Side Effects of Hydroxyzine

Some common side effects of hydroxyzine may include:

  1. Dry mouth
  2. Drowsiness
  3. Fatigue
  4. weakness
  5. Skin rash
  6. Constipation
  7. Headache

Serious side effects are rare but may include the following:

  1. Skin rash
  2. Severe dizziness
  3. Trouble breathing
  4. Seizures
  5. Fast heartbeat
  6. Pus-filled blisters

The above list is not a complete possible side effects. If you experience any of the above or any new symptoms not listed here, contact your doctor immediately so they can provide proper guidance.

You may report to the FDA at 1-800-FDA-1088

9 Important factors to consider before taking hydroxyzine

Some factors to consider before taking hydroxyzine are:

  1. Inform your doctor if you are allergic to hydroxyzine or other antihistamines.
  2. Consult your doctor if you have long QT syndrome (a heart condition) before taking hydroxyzine.
  3. Do not combine hydroxyzine with other drugs or sedatives.
  4. It may cause harm in early pregnancy and may cause birth abnormalities.
  5. Tell your doctor if you are breastfeeding. Hydroxyzine is not usually recommended for breastfeeding mothers. 
  6. Inform your doctor if you have any other medical conditions like heart disease, kidney disease, breathing problems, or glaucoma.
  7. Avoid using alcohol while taking hydroxyzine.
  8. Do not give hydroxyzine to children without a doctor’s approval.
  9. Elderly individuals may be more sensitive to the drug and should not take it without the opinion of a healthcare professional.

Before taking hydroxyzine for sleep, seek medical advice first. Schedule an appointment with a Therapy Fleet authorized professional who, after a comprehensive evaluation, recommends medication to meet your specific needs. 

Conclusion

Hydroxyzine is an antihistamine that has sedative properties and manages anxiety-related insomnia. Before taking Hydroxyzine, always consult a doctor and be aware of its side effects. Individuals with certain medical conditions or those taking other medications should take special precautions.

Hydroxyzine is sometimes prescribed off-label, but it is important to understand that it’s not a long-term solution for sleep-related issues.

 If you are struggling with anxiety and sleep issues, consider speaking with a doctor to determine the best treatment option. Therapy Fleet is a trusted platform to help individuals manage sleep issues, anxiety, and mental health problems.

Start your journey towards better sleep by booking a consultation at Therapy Fleet today!

Not all medications that cause drowsiness are approved as sleep aids — Consult your doctor before use

FAQs

Here are answers to some of the most common questions our therapists receive about Hydroxyzine 

1. What should I know about the storage and disposal of Hydroxyzine?

Store Hydroxyzine in its original container. Keep it at room temperature away from heat, moisture, and light. Keep it out of the reach of children.

For safe disposal, consult your pharmacist. Avoid flushing it. Always store your medications safely and securely. 

2. How quickly does Hydroxyzine help you fall asleep?

Hydroxyzine typically takes 15-30 minutes to start working after ingestion. Individual responses may vary. It is advisable to take Hydroxyzine 30-60 minutes before bedtime to allow its sedative action to take effect.

3. How effective is Hydroxyzine for sleep?

Hydroxyzine has sedative properties that help individuals fall asleep faster and improve sleep quality. Studies show that it shortens the sleep onset time and may increase sleep duration. Thus, it is useful for people who experience sleep issues.

4. How long does Hydroxyzine stay in your system?

Hydroxyzine stays in your system for 3-5 days (70- 125 hours) before being fully cleared from your body. How long it stays in your body depends on various factors, such as dosage, age, liver, and kidney function.

5. Does Hydroxyzine make you sleepy?

Yes, Hydroxyzine may make you drowsy. Do not drive or operate machinery until you know how this medicine can affect you. Drowsiness may vary from person to person and depending on factors such as the individual’s sensitivity to the medication, dosage, and age.

MEDICAL DISCLAIMER 

At TherapyFleet, we strive to enhance the quality of life for those dealing with mental health issues. Our licensed medical professionals meticulously research, edit, and review all content before publication. Nonetheless, this information should not replace professional medical advice, diagnosis, or treatment. For medical guidance, please consult your physician or reach out to Therapy Fleet’s qualified staff.

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